第22回 内藤コンファレンス

ケミカルバイオロジー [I] 天然物化学からの展開

組織委員

セッション

SessionA
Key Natural Products 1

1. Lessons from Studying β- and γ- Peptides

   [Dieter Seebach]

   Laboratorium fur Organische Chemie, Departement fur Chemie undo Angewandte Biowissenschaften, ETH-Zurich, Switzerland

2. Chemical Biology of Plant Movements Using Bioactive Natural Products

   [Minoru Ueda]

   Department of Chemistry, Tohoku University, Japan

3. Quorum Sensing Pheromone, ComX

   [Youji Sakagami]

   Graduate School of Bioagricultural Sciences, Nagoya University, Japan

4. Timer Protein in Diapause Eggs of the Silkworm Bombyx mori Changes its Conformation for Time Measurement

   [Minoru Isobe]

   Institute of Advanced Research, Nagoya University / National Tsing Hua University, Taiwan, Japan

SessionB
Key Natural Products 2

1. Diverse Chemical Structures and Bioactivities of Marine Natural Products

   [Daisuke Uemura]

   Department of Biosciences and Infomatics, Faculty of Science and Technology, Keio University, Japan

2. Herbivore-Induced Volatiles in Plant Defense: Early and late events in Enemy-recognition and response

   [Whilhelm Boland]

   Department of Bioorganic Chemistry, Max Planck Institute for Chemical Ecology, Germany

3. The Ecology, Chemistry, and Evolution of Insect-Bacteria Mutualisms

   [Jon Clardy]

   Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Japan

4. Identification of Bioactive peptides and Proteins that Stimulate the Vomeronasal Pheromone Sensory Pathway for Socio-sexual Communication in Mice

   [Kazushige Touhara]

   Department of Integrated Biosciences, The University of Tokyo, Japan

5. Molecular Mechanisms of Self-incompatibility of Plants

   [Akira Isogai]

   Graduate School of Biological Sciences, Nara Institute of Science and Technology, Japan

SessionC
Bioanalytical Chemistry

1. Capturing the Value of Ultra-High Resolution Tandem Mass Spectrometry in Contemporary Chemical Biology

   [Neil L. Kelleher]

   Department of Chemistry University of Illinois, USA

2. Analyzing Drug Binding Sites in Functionally Competent Membrane Receptors at Sub-Å　Resolution

   [Anthony Watts]

   Biomembrane Structure Unit, Biochemistry Department, Oxford University, UK

3. NMR Approach for Interaction Analysis of Larger Proteins

   [Ichio Shimada]

   Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan

4. Molecular Assemblies in Biomembrances as Viewed by Solid State NMR

   [Michio Murata]

   Department of Chemistry, Graduate School of Science, Osaka University, Japan

5. Color Control Mechanism of Firefly Glowing: Crystal Structure and Mechanism of Luminescent Enzyme Luciferase

   [Hiroaki Kato]

   Department of Structural Biology, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan

SessionD
Small-Molecule-Initiated Biology

1. Design, Synthesis and Application of Bio-imaging Probes which Convert Biological Signals to Chemical Output

   [Kazuya Kikuchi]

   Graduate School of Engineering, Osaka University, Japan

2. New Method for Protein Selective Labeling

   [Itaru Hamachi]

   Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Japan

3. Defining the Druggable Cysteinome

   [Jack Taunton]

   University of California, San Francisco, USA

4. Isolating and Identifying the Targets of Bioactive Small Molecules

   [Motonari Uesugi]

   Institute for Chemical Research and Institute for Integrated Cell-Material Science, Kyoto University, Japan

5. A Small Molecule Approach to Cell Biology

   [Craig M. Crews]

   Departments of Molecular, Cell, and Developmental Biology, Chemistry, and Pharmacology, Yale University, Japan

SessionE
Target Proteins

1. Natural Products as Probes of Eukaryotic Translation

   [Jun O. Liu]

   Departments of Pharmacology and Oncology, Johns Hopkins School of Medicine, USA

2. From Marine Natural Products to Target Proteins: Integrative Approaches in Chemical Biology

   [Hendrik Luesch]

   Department of Medical Chemistry, University of Florida, USA

3. Glyoxalase 1, a Target Molecule of Methyl-Gerfelin which is an Inhibitor of Osteoclastgenesis

   [Hiroyuki Osada]

   Chemical Biology Department, Advanced Science Institute, RIKEN, Japan

4. Mapping Dysregulated Biochemical Pathways in Human Disease by Activity-Based Proteomics and Metabolomics

   [Benjamin F. Cravatt]

   Department of Chemical Physiology, The Scripps Research Institute, USA

5. A New PI3 Kinase Inhibitor ZSTK 474 identified by JFCR39 Cancer Cell Panel

   [Takao Yamori]

   Division of Molecular Pharmacology, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Japan